GP-write is proceeding in phases according to the initial roadmap (White Paper) to evaluate feasibility and value, similar to other large-scale genome projects such as HGP-read, Encyclopedia of DNA Elements (ENCODE), and the Synthetic Yeast Project (Sc2.0). Each of these earlier projects began with pilot projects that focused on a fraction of the genome, typically about 1%. For GP-write, only those projects that are deemed to provide valuable resources for advanced biomedical research and/or biotechnology development will be chosen.
The Scientific Executive Committee evaluates every pilot project submitted. Both approved projects and those currently under review are briefly described below.
Until the project is fully funded, GP-write is supporting the scientists submitting pilot projects with letters of recommendation. In the future, the goal is to financially support the pilot projects directly. There are two ways to apply for a pilot project: 1) Scientists can apply for funding through their university and GP-write will support the project with a Letter of Recommendation, or 2) scientists can partner with the Center of Excellence to apply for funding.
Please contact firstname.lastname@example.org for more information.
Approved Pilot Projects
|Project Lead(s)||Project Title|
|Jef Boeke, NYU Langone Medical Center|
George Church, Harvard Medical School
|Ultra Safe Cell Line|
|Pamela Silver, Wyss Institute|
Jeffrey Way, Wyss Institute
John Glass, J. Craig Venter Institute
|High-throughput HAC Design to Test Connections Between Gene Expression, Location and Conformation|
|Liam Holt, NYU Langone Health||The Seven Signals Toolbox: Leveraging Synthetic Biology to Define the Logic of Stem-Cell Programming|
|Neville Sanjana, New York Genome Center||Precision Human Genome Engineering of Disease-Associated Noncoding Variants|
|Harris Wang, Columbia University||Synthesizing a Prototrophic Human Genome|
|Yasunori Aizawa, Tokyo Institute of Technology||Synthetic Screening for Essential Introns and Retroelements in Human Cell and Animals|
|Matt Maurano, NYU Langone Health||The Dark Matter Project|
Proposed Pilot Projects
— Under Review by Scientific Executive Committee —